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    Nanotechnology Research

    classical_algebra
    classical_algebra
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    Post by classical_algebra Wed Jan 23, 2013 10:41 pm

    I work in a lab in university that experiments with DNA as a building material.
    We focus on the following:

    a) Make DNA nanoconstructions that are more robust with respect to temperature, pH and metal ion concentration -
    allowing them to be used in a wider range of environments

    b) Enable orthogonal chemical and physical stimuli to activate and deactivate DNA sequence-controlled switches -
    enabling greater control of the design and operation of these systems

    c) Develop systems that allow the control of multiple DNA switches without the addition of external reagents -
    enabling the use of these switches in multiplexed self-contained sensing environments

    d) Develop mesoscale DNA constructions that act as sensors

    So far, the lab as created nanoswitches from DNA, controlled by shining light on it.
    http://pubs.rsc.org/en/Content/ArticleLanding/2011/CC/C1CC10292C
    preid1220
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    Post by preid1220 Thu Jan 24, 2013 9:00 am

    How do you monitor the effects and unintended side effects of activating a switch?
    classical_algebra
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    Post by classical_algebra Thu Jan 24, 2013 3:59 pm

    the switches don't actually do anything, they just change DNA structure

    these experiments are done on pure solutions of DNA, in a controlled chemical setting
    its not switching genes on in terms of gene expression, its using DNA as a building material to make swithces for use in
    nanoscale circuit boards and machinery
    Ace
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    Post by Ace Thu Jan 24, 2013 6:55 pm

    Nice! I've been considering taking a career in nanotechnology myself.
    jj16802
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    Post by jj16802 Thu Jan 24, 2013 7:33 pm

    So this can be considered as biological technology?
    Ahmed
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    Post by Ahmed Thu Jan 24, 2013 8:39 pm

    Biochem tech yes
    jj16802
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    Post by jj16802 Fri Jan 25, 2013 1:22 am

    Can't wait till the day I can have a head's up display to remind me of errands and info for tests...

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